Detalhe da pesquisa
1.
Antithrombotic Effects of Combined PAR (Protease-Activated Receptor)-4 Antagonism and Factor Xa Inhibition.
Arterioscler Thromb Vasc Biol
; 40(11): 2678-2685, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32907366
2.
Phase I study of single-dose pharmacokinetics and pharmacodynamics of belatacept in adolescent kidney transplant recipients.
Am J Transplant
; 19(4): 1218-1223, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30582294
3.
Use of a cocktail probe to assess potential drug interactions with cytochrome P450 after administration of belatacept, a costimulatory immunomodulator.
Br J Clin Pharmacol
; 83(2): 370-380, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27552251
4.
Safety, pharmacokinetics, and pharmacodynamics of BMS-986142, a novel reversible BTK inhibitor, in healthy participants.
Eur J Clin Pharmacol
; 73(6): 689-698, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28265691
5.
Maintenance of remission following 2 years of standard treatment then dose reduction with abatacept in patients with early rheumatoid arthritis and poor prognosis.
Ann Rheum Dis
; 74(3): 564-8, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25550337
6.
Model-Based Dose Selection of Subcutaneous Nivolumab in Patients with Advanced Solid Tumors.
Clin Pharmacol Ther
; 115(3): 488-497, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38115195
7.
First-in-human study of deucravacitinib: A selective, potent, allosteric small-molecule inhibitor of tyrosine kinase 2.
Clin Transl Sci
; 16(1): 151-164, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36325947
8.
Evaluation of safety, pharmacokinetics, and pharmacodynamics of apixaban in pediatric subjects at risk of venous or arterial thrombotic disorder.
CPT Pharmacometrics Syst Pharmacol
; 12(4): 500-512, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36861188
9.
Absolute and Relative Bioavailability of Oral Solid Dosage Formulations of Deucravacitinib in Humans.
Clin Pharmacol Drug Dev
; 12(10): 956-965, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37587797
10.
Pharmacokinetics and Safety of the Tyrosine Kinase 2 Inhibitor Deucravacitinib in Healthy Chinese Subjects.
Dermatol Ther (Heidelb)
; 13(12): 3153-3164, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37981596
11.
Single-Dose Pharmacokinetics of Milvexian in Participants with Normal Renal Function and Participants with Moderate or Severe Renal Impairment.
Clin Pharmacokinet
; 61(10): 1405-1416, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35906349
12.
Safety, pharmacokinetics, and pharmacodynamics of milvexian in healthy Japanese participants.
Sci Rep
; 12(1): 5165, 2022 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35338177
13.
Lack of Electrocardiographic Effects of Deucravacitinib in Healthy Subjects.
Clin Pharmacol Drug Dev
; 11(4): 442-453, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35182043
14.
Single-Dose Pharmacokinetics of Milvexian in Participants with Mild or Moderate Hepatic Impairment Compared with Healthy Participants.
Clin Pharmacokinet
; 61(6): 857-867, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35262846
15.
Effects of Itraconazole and Diltiazem on the Pharmacokinetics and Pharmacodynamics of Milvexian, A Factor XIa Inhibitor.
Cardiol Ther
; 11(3): 407-419, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35641780
16.
Effects of rifampin on the pharmacokinetics and pharmacodynamics of milvexian, a potent, selective, oral small molecule factor XIa inhibitor.
Sci Rep
; 12(1): 22239, 2022 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36564395
17.
Model-Based Selection and Recommendation for Subcutaneous Abatacept Dose in Patients With Polyarticular Juvenile Idiopathic Arthritis.
J Clin Pharmacol
; 61(5): 688-699, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33284480
18.
Population pharmacokinetic analysis of ceftobiprole for treatment of complicated skin and skin structure infections.
Antimicrob Agents Chemother
; 53(3): 1228-30, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19075059
19.
Soft-tissue penetration of ceftobiprole in healthy volunteers determined by in vivo microdialysis.
Antimicrob Agents Chemother
; 53(7): 2773-6, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19364847
20.
Population Pharmacokinetics and Exposure-Response Relationship of Intravenous and Subcutaneous Abatacept in Patients With Rheumatoid Arthritis.
J Clin Pharmacol
; 59(2): 245-257, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30229926